Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 17.88
Human Site: S587 Identified Species: 30.26
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 S587 S G A D P V T S V G K R L R P
Chimpanzee Pan troglodytes XP_510208 819 88957 S729 S G A D P V T S V G K R L R P
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 P516 S V G K R L R P L V S T Q P A
Dog Lupus familis XP_548005 637 70371 R554 T S V G K R L R P M V S A Q P
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 S586 N S A D P G T S T G K R L R P
Rat Rattus norvegicus NP_001100231 686 74096 S596 N S A D P G T S M G K R L R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 S592 N I A S P V N S V G K R L R P
Frog Xenopus laevis NP_001088063 660 73751 S574 S A A S R S L S N P V S N A A
Zebra Danio Brachydanio rerio NP_956183 693 76806 A593 N K S N L G L A K P A S L M G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 A579 K S R G N R A A Y D L P G P S
Honey Bee Apis mellifera XP_623775 648 73504 S565 I T S I T K K S R L V K P Q I
Nematode Worm Caenorhab. elegans NP_495526 759 84015 I623 S T S E V S S I E H K P F V P
Sea Urchin Strong. purpuratus XP_794011 768 83924 R656 S Q G A Q L T R A G S L G G V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 N513 E A D I A T G N T S V K K K R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 6.6 6.6 N.A. 73.3 73.3 N.A. N.A. 73.3 20 6.6 N.A. 0 6.6 20 20
P-Site Similarity: 100 100 20 20 N.A. 80 86.6 N.A. N.A. 80 20 33.3 N.A. 6.6 26.6 40 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 43 8 8 0 8 15 8 0 8 0 8 8 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 29 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 8 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 15 15 15 0 22 8 0 0 43 0 0 15 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 8 8 0 15 0 0 0 8 0 0 0 0 0 0 8 % I
% Lys: 8 8 0 8 8 8 8 0 8 0 43 15 8 8 0 % K
% Leu: 0 0 0 0 8 15 22 0 8 8 8 8 43 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 8 0 0 0 8 0 % M
% Asn: 29 0 0 8 8 0 8 8 8 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 36 0 0 8 8 15 0 15 8 15 50 % P
% Gln: 0 8 0 0 8 0 0 0 0 0 0 0 8 15 0 % Q
% Arg: 0 0 8 0 15 15 8 15 8 0 0 36 0 36 8 % R
% Ser: 43 29 22 15 0 15 8 50 0 8 15 22 0 0 8 % S
% Thr: 8 15 0 0 8 8 36 0 15 0 0 8 0 0 0 % T
% Val: 0 8 8 0 8 22 0 0 22 8 29 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _